Our Publications

2017

J.P.B. O’Connor, E.O. Aboagye, J.E. Adams, H.J.W.L. Aerts, S.F. Barrington, A.J. Beer, R. Boellaard, S.E. Bohndiek, M. Brady, G. Brown , D.L. Buckley, T.L. Chenevert, L.P. Clarke, S. Collette, G.J. Cook, N.M. deSouza, J.C. Dickson, C. Dive, J.L. Evelhoch, C. Faivre-Finn, F.A. Gallagher, F.J. Gilbert, R.J. Gillies, V. Goh, J.R. Griffiths, A.M. Groves, S. Halligan, A.L. Harris, D.J. Hawkes, O.S. Hoekstra, E.P. Huang, B.F. Hutton, E.F. Jackson, G.C. Jayson, A. Jones, D.-M. Koh, D. Lacombe, P. Lambin, N. Lassau, M.O. Leach, T.-Y. Lee, E.L. Leen, J.S. Lewis, Y. Liu, M.F. Lythgoe, P. Manoharan, R.J. Maxwell, K.A. Miles, B. Morgan, S. Morris, T. Ng, A.R. Padhani, G.J.M. Parker, M. Partridge, A.P. Pathak, A.C. Peet, S. Punwani, A.R. Reynolds, S.P. Robinson, L.K. Shankar, R.A. Sharma, D. Soloviev, S. Stroobants, D.C. Sullivan, S.A. Taylor, P.S. Tofts, G.M. Tozer, M. van Herk, S. Walker-Samuel, J. Wason, K.J. Williams, P. Workman, T.E. Yankeelov, K. M. Brindle, L.M. McShane, A. Jackson, J.C. Waterton. (2016). Imaging biomarker roadmap for cancer studies. Nat Rev Clin Oncol, 14(3), 169-186, (2017). doi:10.1038/nrclinonc.2016.162

J.C Waterton, M. Ho, L.H. Nordenmark, M. Jenkins, J. DiCarlo, G. Guillard, C. Roberts, G. Buonaccorsi, G.J.M. Parker, M.A. Bowes, C. Peterfy, H. Kellner, P.C. Taylor. Repeatability and response to therapy of dynamic contrast-enhanced magnetic resonance imaging biomarkers in rheumatoid arthritis in a large multicentre trial setting. Eur Radiol, 27(9), 3662-3668, (2017). doi: 10.1007/s00330-017-4736-9.

M.R. Tomaszewski, I.Q. Gonzalez, J.P.B. O’Connor, O. Abeyakoon, G.J.M. Parker, K.J. Williams, F.J. Gilbert, S.E. Bohndiek. Oxygen enhanced optoacoustic tomography (OE-OT) reveals vascular dynamics in murine models of prostate cancer. Theranostics, 7(11), 2900-2913, (2017). doi: 10.7150/thno.19841

C.J. Bajada, R.L. Jackson, H.A. Haroon, H. Azadbakht, G.J.M. Parker, M.A. Lambon Ralph, L.L. Cloutman. A graded tractographic parcellation of the temporal lobe. NeuroImage (In press). doi: 10.1007/s00330-017-4736-9

C.J. Bajada, H.A. Haroon, H. Azadbakht, G.J.M. Parker, M.A. Lambon Ralph, L.L. Cloutman. The tract terminations in the temporal lobe: Their location and associated functions. Cortex (In press). doi: dx.doi.org/10.1016/j.cortex.2016.03.013

F. Zhou, Z. Li, J. Gough, P.L. Hubbard Cristinacce, G.J.M. Parker. Axon mimicking hydrophilic hollow polycaprolactone microfibres for diffusion magnetic resonance imaging. Materials & Design, 137, 394–403, (2018). doi: 10.1016/j.matdes.2017.10.047

A.K. Featherstone, J.P.B. O’Connor, R.A. Little, Y. Watson, S. Cheung, M. Babur, K.J. Williams, J.C. Matthews, G.J.M. Parker. Optimized data-driven mapping of hypoxia-related tumor heterogeneity using DCE-MRI and OE-MRI. Magn. Reson. Med. (in press).

F. Zhou, A. Chirazi, J. Gough, P. Hubbard Cristinacce, G. Parker. Hollow polycaprolactone microspheres with/without single surface hole by co-electrospraying. Langmuir (in press).

K.A. Abid, O.A. Sobowale, L.M. Parkes, J. Naish, G.J.M. Parker, D. du Plessis, D. Brough, J. Barrington, S.M. Allan, R. Hinz, A.R. Parry-Jones. Assessing inflammation in acute intracerebral hemorrhage with PK11195 PET and dynamic contrast-enhanced MRI. J. Neuroimaging (in press).

S. Skeoch, P.L. Hubbard Cristinacce, M. Dobbs, J. Naish, N. Woodhouse, M. Ho, J.C Waterton, G.J.M. Parker, I.N. Bruce. Evaluation of non-contrast MRI biomarkers in lupus nephritis. Clinical and Experimental Rheumatology, (In press).

D.J. McHugh, F.‐L. Zhou, I. Wimpenny, G. Poologasundarampillai, J.H. Naish, P.L. Hubbard Cristinacce, G.J.M. Parker. A biomimetic tumor tissue phantom for validating diffusion‐weighted MRI measurements. Main. Reson. Med. (in press). doi: 10.1002/mrm.27016

R.A. Little, H. Barjat, J.I. Hare, M. Jenner, Y. Watson, S. Cheung, K. Holliday, W. Zhang, J.P.B. O'Connor, S.T. Barry, S. Puri, G.J.M. Parker, J.C. Waterton. Evaluation of dynamic contrast-enhanced MRI biomarkers for stratified cancer medicine: How do permeability and perfusion vary between human tumours? Main. Reson. Imag. (in press). doi: 10.1016/j.mri.2017.11.008

2016

I. Teh, F.-L. Zhou, P.L. Hubbard Cristinacce, G.J.M. Parker, J.E. Schneider. Biomimetic phantom for cardiac diffusion MRI. J Magn. Reson. Imag. 43(3), 594-600, (2016). doi: 10.1002/jmri.25014, Front cover

J.P.B. O’Connor, J.K. Boult, Y. Jamin, M. Babur, K.G. Finegan, K.J. Williams, R.A. Little, A. Jackson, G.J.M.Parker, A.R. Reynolds, J.C. Waterton, S.P. Robinson. Oxygen enhanced MRI accurately identifies, quantifies, and maps hypoxia in preclinical cancer models. Cancer Research 76, 787-795, (2016). doi: 10.1158/0008-5472.CAN-15-2062, Front cover plus editorial.

W.-J.Zhang, R.M. Niven, S.S. Young, Y.-Z. Liu, G.J.M. Parker, J.H. Naish. T1-weighted Dynamic Contrast-enhanced MR Imaging of the Lung in Asthma: Semiquantitative Analysis for the Assessment of Contrast Agent Kinetic Characteristics. Radiology 278(3), 906-916 (2016). doi: 10.1148/radiol.2015141876

D.F. Alamidi, S.S.I. Kindvall, P.L. Hubbard Cristinacce, D.M. McGrath, S.S. Young, J.H. Naish, J.C. Waterton, P. Wo0llmer, S. Diaz, M. Olsson, P.D. Hockings, K.M. Lagerstrand, G.J.M. Parker, L.E. Olsson. T1 Relaxation Time in Lungs of Asymptomatic Smokers. PLoS ONE 11(3), (2016). DOI: doi.org/10.1371/journal.pone.0149760

D.F. Alamidi, A.R. Morgan, P.L. Hubbard Cristinacce, L.H. Nordenmark, P.D. Hockings, K.M. Lagerstrand, S.S. Young, J.H. Naish, J.C. Waterton, N.C. Maguire, L.E. Olsson, G.J.M. Parker. COPD patients have short lung magnetic resonance T1 relaxation time. COPD: J Chronic Obstructuve Pulmonary Disease 13(2). 153-159, (2016). doi:10.3109/15412555.2015.1048851

S.J. Mills, D. du Plessis, P. Pal, G. Thompson, G. Buonaccorsi, C. Soh, G.J.M. Parker, A. Jackson. Mitotic Activity in Glioblastoma Correlates with Estimated Extravascular Extracellular Space Derived from Dynamic Contrast-Enhanced MR Imaging. AJNR American Journal of Neuroradiology 37(5), 811-817, (2016).doi: 10.3174/ajnr.A4623

F.-L. Zhou, P.L. Hubbard Cristinacce, S.J. Eichhorn, G.J.M. Parker. Preparation and characterization of polycaprolactone microspheres by electrospraying. Aerosol Science and Technology, 50(11), 1201-1215, (2016) doi: 10.1080/02786826.2016.1234707

2015

G.Z. Ferl, J.P.B. O’Connor, G.J.M. Parker, R.A.D. Carano, S.J. Acharya, G.C. Jayson, R.E. Port. Mixed-Effects Modeling of Clinical DCE-MRI Data: Application to Colorectal Liver Metastases Treated With Bevacizumab. J. Magn. Reson. Imag. 41(1), 132-141, (2015). doi: 10.1002/jmri.24514.

W.-J. Zhang, R.M. Niven, S.S. Young, Y.-Z. Liud, G.J.M. Parker, J.H. Naish. Dynamic oxygen-enhanced magnetic resonance imaging of the lung in asthma—Initial experience. Eur. J. Radiol. 84(2), 318-326, (2015). doi: 10.1016/j.ejrad.2014.10.021.

P.L. Hubbard, F.-L. Zhou, S.J. Eichhorn, G.J.M. Parker. Biomimetic Phantom for the Validation of Diffusion Magnetic Resonance Imaging. Magn. Reson. Med. 73(1), 299-305, (2015). doi: 10.1002/mrm.25107.

J.P.B. O’Connor, C.J. Rose, J.C. Waterton, R.A.D. Carano, G.J.M. Parker, A. Jackson. Imaging intratumor heterogeneity: Role in therapy response, resistance, and clinical outcome. Clin. Can. Res. 21(2), 249-257, (2015). doi: 10.1158/1078-0432.CCR-14-0990

D.J. McHugh, F. Zhou, P.L. Hubbard Cristinacce, J.H. Naish, G.J.M. Parker. Ground Truth for Diffusion MRI in Cancer: A Model-Based Investigation of a Novel Tissue-Mimetic Material. In S. Ourselin et al. (Eds.): Information Processing in Medical Imaging (IPMI'15), Lect. Notes Comp. Sci. 9123, 179-190, (2015). doi: 10.1007/978-3-319-19992-4_14

N. Muhlert, V. Sethi, L. Cipolotti, H. Haroon, G.J.M. Parker, T. Yousry, C. Wheeler-Kingshott, D. Miller, M. Ron, D. Chard. The grey matter correlates of impaired decision-making in multiple sclerosis. JNNP 86(5), 530-536, (2015). doi: 10.1136/jnnp-2014-308169

I Huen, DM Morris, C Wright, CP Sibley, JH Naish, ED Johnstone. Absence of Po2 change in fetal brain despite Po2 increase in placenta in response to maternal oxygen challenge. BJOG (In press). doi: 10.1111/1471-0528.12804

W.-J. Zhang, P.L. Hubbard Cristinacce, E. Bondesson, L.H. Nordenmark, S.S. Young, Y.-Z. Liu, D. Singh, J.H. Naish, G.J.M. Parker. MR quantitative equilibrium signal mapping: a reliable alternative to CT for the assessment of emphysema in COPD. Radiology 275(2), 579-588, (2015). doi: 10.1148/radiol.14132953.

H. Azadbakht, L.M. Parkes, H.A. Haroon, M. Augath, N.K. Logothetis, A. de Crespigny, H.E. D’Arceuil, G.J.M. Parker. Validation of high-resolution tractography against in vivo tracing in the macaque visual cortex. Cerebral Cortex. 45, 134-136, (2015). doi: 10.1093/cercor/bhu326

H.A.W.M. Tiddens, S.M. Stick, J.M. Wild, P. Ciet, G.J.M. Parker, A. Koch, J. Vogel-Claussen. Respiratory tract exacerbations revisited: Ventilation, Inflammation, Perfusion, and Structure (VIPS) monitoring to redefine treatment. Ped. Pulmonol. 50, S57-S65, (2015). doi: 10.1002/ppul.23266

2014

R.P. Smallman, E. Barkus, H. Azadbakht, K.V. Embleton, H.A. Haroon, S.W. Lewis, D.M. Morris, G.J.M. Parker, T.M. Rushe. MRI diffusion tractography study in individuals with schizotypal features: A pilot study. Psychiatry Research: Neuroimaging. 221(1), 49-57, (2014). doi: 10.1016/j.pscychresns.2013.10.006.

C.J. Rose, J.P.B. O'Connor, T.F. Cootes, C.J. Taylor, G.C. Jayson, G.J.M. Parker, J.C. Waterton. Indexed distribution analysis significance improved significance testing of heterogeneous parameter maps for testing of spatially heterogeneous parameter maps: Application to dynamic contrast‐enhanced MRI biomarkers. Magn. Reson. Med. 71, 1299-1311, (2014). doi: 10.1002/mrm.24755.

M.G. Crabb, J.L. Davidson, R. Little, P. Wright, A.R. Morgan, C.A. Miller, J.H. Naish, G.J.M. Parker, R. Kikinis, H. McCann, W.R.B. Lionheart. Mutual information as a measure of image quality for 3D dynamic lung imaging with EIT. Physiol. Meas. 35, 863-876, (2014). doi: 10.1088/0967-3334/35/5/863

I.V. Linnik, M.L.J. Scott, K. Holliday, N. Woodhouse, J.C. Waterton, J.P.B. O’Connor, H. Barjat, C. Liess, J. Ulloa, H. Young, C. Dive, C.L. Hodgkinson, T. Ward, D. Roberts, S.J. Mills, G. Thompson, G.A. Buonaccorsi, S. Cheung, A. Jackson, J.H. Naish, G.J.M. Parker. Non-invasive tumor hypoxia measurement using magnetic resonance imaging in mouse and human glioblastoma. Magn. Reson. Med. 71(5), 1854-1862, (2014). doi: 10.1002/mrm.24826

M. Lyksborg, H.R. Siebner, P.S. Sorensen, M. Blinkenberg, G.J.M. Parker, A.M. Dogonowski, E. Garde, R. Larsen, T.B. Dyrby. Secondary progressive and relapsing remitting multiple sclerosis leads to motor-related decreased anatomical connectivity. PLoS ONE 9(4), e95540, (2014). doi: 10.1371/journal.pone.0095540.

C.A. Miller, J. Sarma, J.H. Naish, N. Yonan, S.G. Williams, S.M. Shaw, D. Clark, K. Pearce, M. Stout, R. Potluri, A. Borg, G. Coutts, S. Chowdhary, G.P. McCann, G.J.M. Parker, S.G. Ray, M. Schmitt. Multiparametric cardiovascular magnetic resonance assessment of cardiac allograft vasculopathy. J. Amer. Coll. Cardiol. 63(8), 799-808, (2014).

C.A. Miller, J.H. Naish, S.M. Shaw, N. Yonan, S.G. Williams, D. Clark, P.W. Bishop, M.P. Ainslie, A. Borg, G. Coutts, G.J.M. Parker, S.G. Ray, M. Schmitt. Multiparametric cardiovascular magnetic resonance surveillance of acute cardiac allograft rejection and characterisation of transplantation-associated myocardial injury: a pilot study. J. Cardiovasc. Magn. Reson. 16(52),(2014). doi:10.1186/s12968-014-0052-6

C.A Miller, J.H. Naish, M.P. Ainslie, C. Tonge, D. Tout, P. Arumugam, A. Banerji, R.M. Egdell, D. Clark, P. Weale, C.D. Steadman, G.P. McCann, S.G. Ray, G.J.M. Parker, M. Schmitt. Voxel-wise quantification of myocardial blood flow with cardiovascular magnetic resonance: effect of variations in methodology and validation with positron emission tomography. J. Cardiovasc. Magn. Reson. 16(4), (2014). doi: 10.1186/1532-429X-16-11.

A.R. Morgan, G.J.M. Parker, C. Roberts, G.A. Buonaccorsi, N.C. Maguire, P.L. Hubbard Cristinacce, D. Singh, J. Vestbo, L. Bjermer, J. Jögli, Z. Taib, J. Sarv, P.L.B. Bruijnzeel, L.E. Olsson, E. Bondesson, U. Nihlen, D.M. McGrath, S.S. Young, J.C. Waterton, L.H. Nordenmark. Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD. Eur. J. Radiol. 38, 2093-2101, (2014). doi: 10.1016/j.ejrad.2014.08.004 G.Z.

2013

M Bozzali, B Spano, G Parker, G Giuletti, M Castelli, B Basile, S Rossi, L Serra, G Magnani, U Nocentini, C Caltagrione, D Centonze, M Cercignani. Anatomical brain connectivity can assess cognitive dysfunction in multiple sclerosis. Multiple Sclerosis Journal 19(9), 1161-1168, (2013).

CA Miller, J Naish, P Bishop, G Coutts, D Clark, S Zhao, SG Ray, N Yonan, SG Williams, AS Flett, JC Moon, A Greiser, GJM Parker, M Schmitt. Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume. Circ. Cardiovasc. Imaging 6(3), 373-383, (2013). doi: 10.1161/CIRCIMAGING.112.000192.

CA Miller, J Naish, P Bishop, G Coutts, D Clark, S Zhao, SG Ray, N Yonan, SG Williams, AS Flett, JC Moon, A Greiser, GJM Parker, M Schmitt. Response to Letter Regarding Article, "Comprehensive Validation of Cardiovascular Magnetic Resonance Techniques for the Assessment of Myocardial Extracellular Volume". Circ. Cardiovasc. Imaging 6(4), E26-E27, (2013). doi: 10.1161/CIRCIMAGING.113.000583.

Y Assaf, DC Alexander, DK Jones, A Bizzi, TEJ Behrens, CA Clark, Y Cohen, TB Dyrby, PS Huppi, TR Knoesche, D Le Bihan, GJM Parker. The CONNECT project: Combining macro- and micro-structure. NeuroImage 80, 273-282, (2013). doi: 10.1016/j.neuroimage.2013.05.055.

N Muhlert, V Sethi, T Schneider, P Daga, L Cipolotti, HA Haroon, GJM Parker, S Ourselin, CAM Wheeler-Kingshott, DH Miller, MA Ron, DT Chard. Diffusion MRI-based cortical complexity alterations associated with executive function in multiple sclerosis. J. Magn. Reson. Imag. 38(1), 54-63, (2013). doi: 10.1002/jmri.23970.

L Horsley, J Cummings, M Middleton, T Ward, A Backen, A Clamp, M Dawson, H Farmer, N Fisher, G Halbert, S Halford, A Harris, J Hasan, P Hogg, G Kumaran, R Little, GJM Parker, P Potter, M Saunders, C Roberts, D Shaw, N Smith, J Smythe, A Taylor, H Turner, Y Watson, C Dive, GC Jayson. A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology, 72(6), 1343-1352, (2013). doi: 10.1007/s00280-013-2320-9.

LL Cloutman, RJ Binney, DM Morris, GJM Parker, MA Lambon Ralph. Using in vivo probabilistic tractography to reveal two segregated dorsal ‘language-cognitive’ pathways in the human brain. Brain and Language 127(2), 230–240, (2013). dii: 10.1016/j.bandl.2013.06.005

M Bozzali, GJM Parker, B Spano, L serra, G Giulietti, R Perri, G Magnani, C Marra, MG Vita, C Caltagirone, M Cercignani. Brain tissue modifications induced by cholinergic therapy in Alzheimer’s disease. Human Brain Mapping 34(12), 3158-3167, (2013). doi: 10.1002/hbm.22130.

I Huen, DM Morris, C Wright, GJM Parker, CP Sibley, ED Johnstone, JH Naish. R1 and R2* changes in the human placenta in response to maternal oxygen challenge. Magn. Reson. Med. 70(5), 1427-1433, (2013). doi: 10.1002/mrm.24581.

2012

A. Banerji, J.H. Naish, Y. Watson, G.C. Jayson, G.A. Buonaccorsi, G.J.M. Parker. DCE-MRI model selection for investigating disruption of microvascular function in livers with metastatic disease. J. Magn. Reson. Imag. 35(1), 196-203, (2012).

J.L. Davison, R.A. Little, P. Wright, J. Naish, R. Kikinis, G.J.M. Parker, H. McCann. Fusion of images obtained from EIT and MRI. Electronics Letters 48(11), 617-618, (2012).

L.L. Cloutman, R.J. Binney, M. Drakesmith, G.J. Parker, M.A. Lambon-Ralph. The variation of function across the human insula mirrors its patterns of structural connectivity: Evidence from in vivo probabilistic tractography. NeuroImage 59(4), 3514-3521, (2012).

M.O. Leach, B. Morgan, P.S. Tofts, D.L. Buckley, W. Huang, M.A. Horsfield, T.L. Chenevert, D.J. Collins, A. Jackson, D. Lomas, B. Whitcher, L. Clarke, R. Plummer, I. Judson, R. Jones, R. Alonzi, T. Brunner, D.M. Koh, P. Murphy, J.C. Waterton, G. Parker, M.J. Graves, T.W.J. Scheenen. T.W. Redpath. M. Orton, G. Karczmar, H. Huisman, J. Barentsz, A. Padhani, on behalf of the Experimental Cancer Medicine Centres Imaging Network Steering Committee. Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging. Eur. Radiol. 22, 1451-1464, (2012).

R.J. Binney, G.J.M. Parker, M.A. Lambon Ralph. Convergent connectivity and graded specialization in the rostral human temporal lobe as revealed by diffusion weighted imaging probabilistic tractography. J Cognitive Neurosci. 24(10), 1998-2014, (2012). M. Cercignani, K. Embleton, G.J.M. Parker, M. Bozzali. Group-averaged anatomical connectivity mapping for improved human white matter pathway visualisation. NMR in Biomed. 25(11), 1224-1233, (2012).

F.-L. Zhou, P.L. Hubbard, S.J. Eichhorn, G.J.M. Parker. Coaxially electrospun axon-mimicking fibers for diffusion magnetic resonance imaging. ACS Applied Materials & Interfaces 4, 6311-6316, (2012).

2011

Y. Iturria-Medina, A.P. Fernández, D.M. Morris, E.J. Canales-Rodríguez, H.A. Haroon, L. Pentón, M. Augath, L. García, N. Logothetis, G.J.M. Parker, L, Melie-García. Brain Hemispheric Structural Efficiency and Interconnectivity Rightward Asymmetry in Human and Nonhuman Primates. Cereb. Cortex 21(1), 56-67, (2011). doi:10.1093/cercor/bhq058

C. Roberts, R. Little, Y. Watson, S. Zhao, D.L. Buckley, G.J.M. Parker. The effect of blood inflow and B1-field inhomogeneity on measurement of the arterial input function in axial 3D spoiled gradient echo dynamic contrast-enhanced MRI. Magn. Reson. Med. 65(1), 108-119, (2011). doi: 10.1002/mrm.22593

M. Bozzali, G.J.M. Parker, L. Serra, K. Embleton, T. Gill, R. Perri, C. Caltagirone, M. Cercignani. Anatomical connectivity mapping: A new tool to assess brain disconnection in Alzheimer's disease. NeuroImage 54(3), 2045-2051, (2011).

H. Zhang, P.L. Hubbard, G.J.M. Parker, D.C. Alexander. Axon diameter mapping in the presence of orientation dispersion with diffusion MRI. NeuroImage 56,1301–1315, (2011).

J.P.B. O’Connor, C.J. Rose, A. Jackson, Y. Watson, S. Cheung, G.C. Jayson, F. Maders, B.J. Whitcher, C. Roberts, G.A. Buonaccorsi, G. Thompson, G.J.M. Parker. DCE-MRI biomarkers of microvascular structure and function predict CRC liver metastasis shrinkage induced by bevacizumab and FOLFOX-6. Brit. J. cancer. 105, 139-145, (2011).

J.H. Naish, D.M. McGrath, L.J. Bains, K. Passera, C. Roberts, Y. Watson, S. Cheung, M.B. Taylor, J.P. Logue, D.L. Buckley, J. Tessier, H. Young, J.C. Waterton, G.J.M. Parker. Comparison of dynamic contrast-enhanced MRI and dynamic contrast-enhanced CT biomarkers in bladder cancer. Magn. Reson. Med. 66(1), 219-226, (2011). doi: 10.1002/mrm.22774

F.-L. Zhou, P.L. Hubbard, S.J. Eichhorn, G.J.M. Parker. Jet deposition in near-field electrospinning of patterned single component and core-shell fibres. Polymer 52(16), 3603-3610,(2011).

C.L. Mitchell, J.P.B. O’Connor, C. Roberts, Y. Watson, A. Jackson, S. Cheung, J. Evans, J. Spicer, A. Harris, C. Kelly, S. Rudman, M. Middleton, A. Fielding, J. Tessier, H. Young, G.J.M. Parker, G.C. Jayson. A two-part Phase II study of cediranib in patients with advanced solid tumours: the effect of food on single-dose pharmacokinetics and an evaluation of safety, efficacy and imaging pharmacodynamics. Cancer Chemother. Pharmacol. 68(3), 631–641, (2011). doi: 10.1007/s00280-010-1534-3

C. Wright, D.M. Morris, P.N. Baker, I.P. Crocker, P.A. Gowland, G.J. Parker, C.P. Sibley. Magnetic resonance imaging relaxation time measurements of the placenta at 1.5T. Placenta 32(12), 1010-1015, (2011).

2010

S.J. Mills, C. Soh, C.J. Rose, S. Cheung, S. Zhao, G.J. Parker, A. Jackson. Candidate biomarkers of extravascular extracellular space: a direct comparison of apparent diffusion coefficient and dynamic contrast-enhanced MR imaging--derived measurement of the volume of the extravascular extracellular space in glioblastoma multiforme. AJNR Am. J. Neuroradiol. 31(3), 549-553, (2010).

S.J. Mills, C. Soh, J.P.B. O’Connor, C.J. Rose, G. Buonaccorsi, S. Cheung, S. Zhao, G.J.M. Parker, A. Jackson. Enhancing fraction in glioma and its relationship to the tumoral vascular microenvironment: A dynamic contrast-enhanced MR imaging study. AJNR Am. J. Neuroradiol. 31(4), 726-731, (2010).

M. Visser, K.V. Embleton, E. Jefferies, G.J. Parker, M.A. Lambon Ralph. The inferior, anterior temporal lobes and semantic memory clarified: Novel evidence from distortion-corrected fMRI. Neuropsychologia 48(6), 1689-1696, (2010).

L.J. Bains, D.M. McGrath, J.H. Naish, S. Cheung, Y. Watson, M.B. Taylor, J.P. Logue, G.J.M. Parker, J.C. Waterton, D.L. Buckley. Tracer kinetic analysis of dynamic contrast-enhanced MRI and CT data: A preliminary comparison to assess the magnitude of water exchange effects. Magn. Reson. Med. 64(2), 595–603, (2010).

D.C. Alexander, P.L. Hubbard, M.G. Hall, E.A. Moore, M. Ptito, G.J.M. Parker, T.B. Dyrby. Orientationally invariant indices of axon diameter and density from diffusion MRI. NeuroImage 52(4), 1374-1389, (2010).

J.H. Naish, C.E. Hutchinson, A. Caunce, C. Roberts, J.C. Waterton, P.D. Hockings, C.J. Taylor, G.J.M. Parker. Multiple-Bolus Dynamic Contrast-Enhanced MRI in the Pancreas During a Glucose Challenge. J. Magn. Reson. Imag. 32(3), 622-628, (2010).

K.V. Embleton, H.A. Haroon, D.M. Morris, M.A. Lambon Ralph, G.J.M. Parker. Distortion correction for diffusion-weighted MRI tractography and fMRI in the temporal lobes. Hum. Brain Mapp. 31(10), 1570-1587, (2010).

R.J. Binney, K.V. Embleton, E. Jefferies, G.J.M. Parker, M.A. Lambon Ralph. The ventral and inferolateral apsects of the anterior temporal lobe are crucial in semantic memory: Evidence from a novel direct comparison of distortion-corrected fMRI, rTMS and semantic dementia. Cerebral Cortex 20(11), 2728-2738, (2010). [doi:10.1093/cercor/bhq019]

C.L. Mitchell, J.P. O'Connor, A. Jackson, G.J. Parker, C. Roberts, Y. Watson, S. Cheung, K. Davies, G.A. Buonaccorsi, A.R. Clamp, J. Hasan, L. Byrd, A. Backen, C. Dive, G.C. Jayson. Identification of early predictive imaging biomarkers and their relationship to serological angiogenic markers in patients with ovarian cancer with residual disease following cytotoxic therapy. Ann. Oncol. 21(10), 1982-1989, (2010).

L.E. Kershaw, J.H. Naish, D.M. McGrath, J.C. Waterton, G.J.M. Parker. Measurement of arterial plasma oxygenation in dynamic oxygen-enhanced MRI. Magn. Reson. Med. 64, 1838–1842, (2010).

2009

J.B.P. O'Connor, J.H. Naish, A. Jackson, J.C. Waterton, Y. Watson, S. Cheung, D.L. Buckley, D.M. McGrath, G.A. Buonaccorsi, S.J. Mills, C. Roberts, G.C. Jayson, G.J.M. Parker. Comparison of normal tissue R1 and R2* modulation by oxygen and carbogen. Magn. Reson. Med. 61, 75-83, (2009)

H.A. Haroon, D.M. Morris, K.V. Embleton, D.C. Alexander, G.J.M. Parker. Using the model-based residual bootstrap to quantify uncertainty in fiber orientations from q-ball analysis. IEEE Trans. Med. Imag. 28(4), 535-550, (2009).

D.M. McGrath, D.P. Bradley, J.L. Tessier, T. Lacey, C.J. Taylor, G.J.M. Parker. Comparison of model-based arterial input functions for dynamic contrast-enhanced MRI in tumor bearing rats. Magn. Reson. Med. 61, 1173-1184, (2009).

S.J. Mills, C. Soh, J.P.B. O’Connor, C.J. Rose, G. Buonaccorsi, S. Cheung, S. Zhao, G.J.M. Parker, A. Jackson. Tumour Enhancing Fraction (EnF) in Glioma: Relationship to Tumour Grade. Eur. Radiol. 19(6), 1489-1498. (2009)

J.N. Naish, L.E. Kershaw, D.L. Buckley, A. Jackson, J.C. Waterton, G.J.M. Parker. Modelling of contrast agent kinetics in the lung using T1-weighted dynamic contrast-enhanced MRI. Magn. Reson. Med. 61(6), 1507-1514, (2009).

M. Yogarajah, F. Niels, S. Bonelli, M. Cercignani, J. Acheson, G.J.M. Parker, D.C. Alexander, A. McEvoy, M. Symms, M. Koepp, J. Duncan. Defining Meyer’s loop – temporal lobe resections, visual field deficits and diffusion tensor tractography. Brain 132, 1656-1668. (2009).

C.J. Rose, S.J. Mills, J.P.B. O’Connor, G.A. Buonaccorsi, C. Roberts, S. Cheung, S. Zhao, B. Whitcher, G.J.M. Parker. Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps. Magn. Reson. Med. 62, 488-499, (2009).

J.P.B. O’Connor, J.H. Naish, G.J. M. Parker, J.C. Waterton, Y. Watson, G.C. Jayson, Ph.D., G.A. Buonaccorsi, S. Cheung, D.L. Buckley, D.M. Mcgrath, C.M.L. West, S.E. Davidson, C. Roberts, S.J. Mills, C.L. Mitchell, L. Hope, N.C. Ton, A Jackson. Preliminary study of oxygen-enhanced longitudinal relaxation In MRI: A potential novel biomarker of oxygenation changes in solid tumors. Int. J. Radiat. Oncol. Biol. Phys. 75(4), 1209-1215, (2009).

J.B.P. O’Connor, R.A.D. Carano, A.R. Clamp, J. Ross, C.C.K. Ho, A. Jackson, G.J.M. Parker, C.J. Rose, F.V. Peale, M. Friesenhahn, C.L. Mitchell, Y. Watson, C. Roberts, L. Hope, S. Cheung, H.B. Reslan, M.A.T. Go, G.J. Pacheco, X. Wu, T.C. Cao, S. Ross, G.A. Buonaccorsi, K. Davies, J. Hasan, P. Thornton, O. del Puerto, N. Ferrara, N. van Bruggen, G.C. Jayson. Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor. Clin. Cancer. Res. 15(21), 6674-6682, (2009).

2008

Caleb Roberts, Geoff J. M. Parker, Chris J. Rose, Yvonne Watson, James P. O'Connor, Stavros M. Stivaros, Alan Jackson, and Vivian E. Rushton. Glandular Function in Sjögren Syndrome: Assessment with Dynamic Contrast-enhanced MR Imaging and Tracer Kinetic Modeling—Initial Experience.Magn. Reson. Med. 246(3): 845–53, 2008.

McGrath DM, Naish JH, O'Connor JP, Hutchinson CE, Waterton JC, Taylor CJ, Parker GJ. Oxygen-induced changes in longitudinal relaxation times in skeletal muscle. Magn. Reson. Med. 26(2): 221–7, 2008.

Deirdre M. McGrath, Josephine H. Naish, James P.B. O'Connor, Charles E. Hutchinson, John C. Waterton, Chris J. Taylor and Geoffrey J.M. Parker. Oxygen-induced changes in longitudinal relaxation times in skeletal muscle.Magnetic Resonance Imaging 26(2): 221–7, 2008.

James PB O'Connor, Alan Jackson, Marie-Claude Asselin, David L Buckley, Geoff JM Parker, Gordon C Jayson. Quantitative Imaging Biomarkers in the Clinical Development of Targeted Therapeutics: Current and Future Perspectives.The Lancet Oncology 9(7): 1489-1498, 2008.

James P.B. O'Connor 1 2, Josephine H. Naish, Alan Jackson, John C. Waterton, Yvonne Watson, Sue Cheung, David L. Buckley, Deirdre M. McGrath, Giovanni A. Buonaccorsi, Samantha J. Mills, Caleb Roberts, Gordon C. Jayson, Geoff J.M. Parker. Comparison of normal tissue R1 and R2* modulation by oxygen and carbogen. Magnetic Resonance in Medicine 61(1): 75–83, 2008.

2007

John P. Carr, David L. Buckley, Jean Tessier, Geoff J.M. Parker. What levels of precision are achievable for quantification of perfusion and capillary permeability surface area product using ASL?. Mag. Reson. Med. 58(2): 281–9, 2007.

J.P.B. O’Connor, A. Jackson, G.A. Buonaccorsi, Y. Watson, S. Cheung, C. Roberts, D.M. McGrath, J.H Naish, C. Rose, P.M. Dark, G.C. Jayson, D.L. Buckley, G.J.M. Parker. Organ-specific effects of oxygen and carbogen gas inhalation on tissue longitudinal relaxation times. Magn. Reson. Med. 58(3): 490–496, 2007.

G.A. Buonaccorsi, J.P.B. O’Connor, A. Caunce, C. Roberts, S. Cheung, Y. Watson, K. Davies, A. Jackson, G.C. Jayson, G.J.M. Parker. Tracer kinetic model driven registration for DCE-MRI time-series data. Clin. Cancer Res. 58(5): 1010–9, 2007.

James P.B. O'Connor, Gordon C. Jayson, Alan Jackson, Dana Ghiorghiu, Bernadette M. Carrington, Chris J. Rose, Samantha J. Mills, Ric Swindell, Caleb Roberts, Claire L. Mitchell and Geoffrey J.M. Parker. Enhancing Fraction Predicts Clinical Outcome following First-Line Chemotherapy in Patients with Epithelial Ovarian Carcinoma. Clin. Cancer Res. 13(N/A): 6130–5, 2007.

Alan Jackson, James P.B. O'Connor, Geoff J.M. Parker and Gordon C. Jayson.Imaging Tumor Vascular Heterogeneity and Angiogenesis using Dynamic Contrast-Enhanced Magnetic Resonance Imaging. Clin. Cancer Res. 13(N/A): 3449–59, 2007.

J P B O'Connor, A Jackson, G J M Parker and G C Jayson. DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents. Brit. J. Cancer 96(N/A): 189–95, 2007.

Saifee A. Mullamitha, Nhuan C. Ton, Geoff J.M. Parker, Alan Jackson, Peter J. Julyan, Caleb Roberts, Gio A. Buonaccorsi, Yvonne Watson, Karen Davies, Sue Cheung, Lynn Hope, Juan W. Valle, John A. Radford, Jeremy Lawrance, Mark P. Saunders, Mihaela C. Munteanu, Marian T. Nakada, Jeffrey A. Nemeth, Hugh M. Davis, Qun Jiao, Uma Prabhakar, Zhihui Lang, Robert E. Corringham, Robert A. Beckman, Gordon C. Jayson in association with the Biotherapy Development Association. Phase I Evaluation of a Fully Human Anti–αv Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors.Clin. Cancer Res. 13(N/A): 2128–35, 2007.

N.C. Ton, G.J. Parker, A. Jackson, S. Mullamitha, G.A. Buonaccorsi, C. Roberts, Y. Watson, K. Davies, S. Cheung, L. Hope, F. Power, J. Lawrance, J. Valle, M. Saunders, R. Felix, J.A. Soranson, L. Rolfe, K. Zinkewich-Peotti, G.C. Jayson.Phase I Evaluation of CDP791, a PEGylated Di-Fab' Conjugate that Binds Vascular Endothelial Growth Factor Receptor 2. Clin. Cancer Res. 13(N/A): 7113–8, 2007.

2006

Geoff J.M. Parker, Caleb Roberts, Andrew Macdonald, Giovanni A. Buonaccorsi, Sue Cheung, David L. Buckley, Alan Jackson, Yvonne Watson, Karen Davies, Gordon C. Jayson. Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI. Mag. Reson. Med. 56(5): 993–1000, 2006.

Caleb Roberts, David L. Buckley, Geoff J.M. Parker. Comparison of errors associated with single- and multi-bolus injection protocols in low-temporal-resolution dynamic contrast-enhanced tracer kinetic analysis. Mag. Reson. Med. 56(3): 611–9, 2006.

Giovanni A. Buonaccorsi, Caleb Roberts, Sue Cheung, Yvonne Watson, James P.B. O’Connor, Karen Davies, Alan Jackson, Gordon C. Jayson, Geoff J.M. Parker. Comparison of the Performance of Tracer Kinetic Model-Driven Registration for Dynamic Contrast Enhanced MRI Using Different Models of Contrast Enhancement. Acad. Radiology 13(9): 1112–1123, 2006.

Caleb Roberts, Basma Issa, Andrew Stone, Alan Jackson, John C. Waterton, Geoffrey J.M. Parker. Comparative study into the robustness of compartmental modeling and model-free analysis in DCE-MRI studies. J. Mag. Reson. Imag. 23(4): 554–63, 2006.

S.J. Mills, T.A. Patankar, H.A. Haroon, D. Balériaux, R. Swindell and A. Jackson.Do Cerebral Blood Volume and Contrast Transfer Coefficient Predict Prognosis in Human Glioma?. Am. J. Neuroradiology 27(N/A): 853–8, 2006.

2005

Tufail F. Patankar, Hamied A. Haroon, Samantha J. Mills, Danielle Balériaux, David L. Buckley, Geoff J.M. Parker and Alan Jackson. Is Volume Transfer Coefficient (Ktrans) Related to Histologic Grade in Human Gliomas?. Am. J. Neuroradiology 26(N/A): 2455–65, 2005.

Josephine H. Naish, Geoffrey J. M. Parker, Paul C. Beatty, Alan Jackson, Simon S. Young, John C. Waterton, Chris J. Taylor. Improved quantitative dynamic regional oxygen-enhanced pulmonary imaging using image registration.Mag. Reson. Med. 54(2): 464–9, 2005.

G.C. Jayson, G.J.M. Parker, S. Mullamitha, J.W. Valle, M. Saunders, L. Broughton, J. Lawrance, B. Carrington, C. Roberts, B. Issa, D.L. Buckley, S. Cheung, K. Davies, Y. Watson, K. Zinkewich-Péotti, L. Rolfe, A. Jackson.Blockade of Platelet-Derived Growth Factor Receptor-Beta by CDP860, a Humanized, PEGylated di-Fab', Leads to Fluid Accumulation and Is Associated With Increased Tumor Vascularized Volume. J. Clin. Oncology 23(5): 973–81, 2005.

2004

Harrer JU, Parker GJ, Haroon HA, Buckley DL, Embelton K, Roberts C, Balériaux D, Jackson A. Comparative study of methods for determining vascular permeability and blood volume in human gliomas. J. Mag. Reson. Imag. 20(5): 748–57, 2004.

David L. Buckley, Caleb Roberts, Geoff J. M. Parker, John P. Logue and Charles E. Hutchinson. Prostate Cancer: Evaluation of Vascular Characteristics with Dynamic Contrast-enhanced T1-weighted MR Imaging—Initial Experience.Radiology 223(3): 709–15, 2004.

2002

Neil G. Harris, Victoria Gauden, Paul A. Fraser, Stephen R. Williams, Geoff J. M. Parker. MRI measurement of blood-brain barrier permeability following spontaneous reperfusion in the starch microsphere model of ischemia. J. Mag. Reson. Imag. 20(3): 221–30, 2002.

 

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